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Rick T Owens Selected Research

Decorin

4/2014Biglycan and decorin differentially regulate signaling in the fetal membranes.
4/2014Reprint of: Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells.
2/2014Decorin induces mitophagy in breast carcinoma cells via peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) and mitostatin.
2/2014Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells.
5/2013Decorin potentiates interferon-γ activity in a model of allergic inflammation.
5/2013Decorin induces rapid secretion of thrombospondin-1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho-associated coiled-coil containing protein kinase 1.
2/2012Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3.
1/2012Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model.
1/2012The dermatan sulfate proteoglycan decorin modulates α2β1 integrin and the vimentin intermediate filament system during collagen synthesis.
12/2010Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels.
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Rick T Owens Research Topics

Disease

13Neoplasms (Cancer)
04/2014 - 02/2005
8Breast Neoplasms (Breast Cancer)
02/2014 - 02/2005
2Ehlers-Danlos Syndrome (Syndrome, Ehlers-Danlos)
04/2014 - 01/2012
2Hypoxia (Hypoxemia)
05/2013 - 02/2012
2Prostatic Neoplasms (Prostate Cancer)
10/2010 - 10/2009
2Carcinoma (Carcinomatosis)
09/2008 - 02/2005
1Premature Birth (Birth, Premature)
04/2014
1Hypersensitivity (Allergy)
05/2013
1Edema (Dropsy)
05/2013
1Inflammation (Inflammations)
05/2013
1Carcinogenesis
01/2012
1cyclopia sequence
04/2009
1Muscular Dystrophies (Muscular Dystrophy)
11/2006
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
09/2006
1Neoplasm Metastasis (Metastasis)
02/2005

Drug/Important Bio-Agent (IBA)

17DecorinIBA
04/2014 - 02/2005
8Proteins (Proteins, Gene)FDA Link
02/2014 - 02/2005
7Phosphotransferases (Kinase)IBA
04/2014 - 09/2008
5Small Leucine-Rich ProteoglycansIBA
04/2014 - 05/2009
5tyrosine receptor (receptor, tyrosine)IBA
04/2014 - 12/2010
5ErbB Receptors (EGF Receptor)IBA
10/2009 - 02/2005
4Proteoglycans (Proteoglycan)IBA
04/2014 - 04/2009
3Docosahexaenoic AcidsIBA
10/2011 - 04/2008
3Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
10/2011 - 04/2008
3Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA
10/2011 - 04/2008
2Syndecan-1 (Syndecan 1)IBA
10/2011 - 04/2008
1BiglycanIBA
04/2014
1Mitochondrial DNA (mtDNA)IBA
02/2014
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
02/2014
1InterferonsIBA
05/2013
1CytokinesIBA
05/2013
1angiokinesIBA
05/2013
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2012
1Dermatan SulfateIBA
01/2012
1Biological ProductsIBA
01/2012
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
10/2011
1CateninsIBA
12/2010
1Coloring Agents (Dyes)IBA
12/2010
1Androgen Receptors (Androgen Receptor)IBA
10/2009
1Epidermal Growth Factor (EGF)IBA
10/2009
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
05/2009
1Messenger RNA (mRNA)IBA
04/2009
1AG-879IBA
09/2008
1PPAR gammaIBA
04/2008
1Dystrophin-Associated Protein ComplexIBA
11/2006
11,2- diarachidonoyl- glycero- 3- phosphocholineIBA
11/2006
1Caspase 3 (Caspase-3)IBA
09/2006
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
09/2005

Therapy/Procedure

2Therapeutics
10/2009 - 02/2005
1Intraperitoneal Injections
09/2006